| 1. Identity statement | ||||
| Reference Type | Journal Article | |||
| Site | mtc-m21c.sid.inpe.br | |||
| Holder Code | isadg {BR SPINPE} ibi 8JMKD3MGPCW/3DT298S | |||
| Identifier | 8JMKD3MGP3W34R/44QAPC5 | |||
| Repository | sid.inpe.br/mtc-m21c/2021/06.02.12.59 (restricted access) | |||
| Last Update | 2021:06.02.12.59.41 (UTC) simone | |||
| Metadata Repository | sid.inpe.br/mtc-m21c/2021/06.02.12.59.41 | |||
| Metadata Last Update | 2024:05.08.19.55.15 (UTC) simone | |||
| DOI | 10.1007/s00784-020-03633-6 | |||
| ISSN | 1432-6981 | |||
| Citation Key | SatoRMMRMVLBB:2021:RoNaMo | |||
| Title | The role of nanohydroxyapatite on the morphological, physical, and biological properties of chitosan nanofibers  | |||
| Year | 2021 | |||
| Month | May | |||
| Access Date | 2024, May 09 | |||
| Type of Work | journal article | |||
| Secondary Type | PRE PI | |||
| Number of Files | 1 | |||
| Size | 1173 KiB | |||
| 2. Context | ||||
| Author | 1 Sato, Tabata P. 2 Rodrigues, Bruno V. M. 3 Mello, Daphne C. R. 4 Münchow, Eliseu A. 5 Ribeiro, Juliana S. 6 Machado, João Paulo Barros 7 Vasconcellos, Luana M. R. 8 Lobo, Anderson de Oliveira 9 Bottino, Marco C. 10 Borges, Alexandre L. S. | |||
| Resume Identifier | 1 2 3 4 5 6 8JMKD3MGP5W/3C9JHER | |||
| ORCID | 1 2 3 4 5 6 7 8 9 0000-0001-8740-2464 | |||
| Group | 1 2 3 4 5 6 COPDT-CGIP-INPE-MCTI-GOV-BR | |||
| Affiliation | 1 Universidade Estadual Paulista (UNESP) 2 Universidade Brasil 3 Universidade Estadual Paulista (UNESP) 4 Universidade Federal do Rio Grande do Sul (UFRGS) 5 University of Michigan School of Dentistry 6 Instituto Nacional de Pesquisas Espaciais (INPE) 7 Universidade Estadual Paulista (UNESP) 8 Universidade Brasil 9 University of Michigan School of Dentistry 10 Universidade Estadual Paulista (UNESP) | |||
| Author e-Mail Address | 1 2 3 4 5 6 machadopaulo@gmail.com 7 8 9 mbottino@umich.edu 10 alexandre.borges@unesp.br | |||
| Journal | Clinical Oral Investigations | |||
| Volume | 25 | |||
| Number | 5 | |||
| Pages | 3095-3103 | |||
| Secondary Mark | A2_ODONTOLOGIA A2_MEDICINA_VETERINÁRIA A2_INTERDISCIPLINAR A2_ENGENHARIAS_II B1_SAÚDE_COLETIVA B1_QUÍMICA B1_MEDICINA_II B1_MEDICINA_I B1_MATERIAIS B1_FARMÁCIA B1_CIÊNCIAS_BIOLÓGICAS_II B1_CIÊNCIAS_BIOLÓGICAS_I B2_CIÊNCIAS_BIOLÓGICAS_III B2_ASTRONOMIA_/_FÍSICA | |||
| History (UTC) | 2021-06-02 13:01:39 :: simone -> administrator :: 2021 2022-04-03 23:14:35 :: administrator -> simone :: 2021 | |||
| 3. Content and structure | ||||
| Is the master or a copy? | is the master | |||
| Content Stage | completed | |||
| Transferable | 1 | |||
| Content Type | External Contribution | |||
| Version Type | publisher | |||
| Keywords | Antimicrobial Chitosan Electrospinning Regeneration Regenerative dentistry Scaffolds | |||
| Abstract | Objectives: This study aimed to evaluate the effects of nanohydroxyapatite (nHAp) particles on the morphological, chemical, physical, and biological properties of chitosan electrospun nanofibers. Materials and methods: nHAp particles with a 1.67 Ca/P ratio were synthesized via the aqueous precipitation method, incorporated into chitosan polymer solution (0.5 wt%), and electrospun into nHAp-loaded fibers (ChHa fibers). Neat chitosan fibers (nHAp-free, Ch fibers) were used as the control. The electrospun fiber mats were characterized using morphological, topographical, chemical, thermal, and a range of biological (antibacterial, antibiofilm, cell viability, and alkaline phosphatase [ALP] activity) analyses. Data were analyzed using ANOVA and Tukeys test (α = 0.05). Results: ChHa fibers demonstrated a bead-like morphology, with thinner (331 ± 110 nm) and smoother (Ra = 2.9 ± 0.3 μm) distribution as compared to the control fibers. Despite showing similar cell viability and ALP activity to Ch fibers, the ChHa fibers demonstrated greater antibacterial potential against most tested bacteria (except for P. intermedia), and higher antibiofilm activity against P. gingivalis biofilm. Conclusions: The incorporation of nHAp particles did not jeopardize the overall morphology, topography, physical, and biological characteristics of the chitosan nanofibers. Clinical relevance: The combination of nHAp particles with chitosan can be used to engineer bioactive, electrospun composite nanofibers with potential applications in regenerative dentistry. © 2020, Springer-Verlag GmbH Germany, part of Springer Nature. | |||
| Area | FISMAT | |||
| Arrangement | urlib.net > BDMCI > CGIP > The role of... | |||
| doc Directory Content | access | |||
| source Directory Content | there are no files | |||
| agreement Directory Content |
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| 4. Conditions of access and use | ||||
| Language | en | |||
| Target File | Sato_role.pdf | |||
| User Group | simone | |||
| Reader Group | administrator simone | |||
| Visibility | shown | |||
| Read Permission | deny from all and allow from 150.163 | |||
| Update Permission | not transferred | |||
| 5. Allied materials | ||||
| Next Higher Units | 8JMKD3MGPCW/46KUES5 | |||
| Citing Item List | sid.inpe.br/bibdigital/2022/04.03.23.11 3 | |||
| Dissemination | WEBSCI; PORTALCAPES; COMPENDEX; SCOPUS. | |||
| Host Collection | urlib.net/www/2017/11.22.19.04 | |||
| 6. Notes | ||||
| Empty Fields | alternatejournal archivingpolicy archivist callnumber copyholder copyright creatorhistory descriptionlevel e-mailaddress format isbn label lineage mark mirrorrepository nextedition notes parameterlist parentrepositories previousedition previouslowerunit progress project rightsholder schedulinginformation secondarydate secondarykey session shorttitle sponsor subject tertiarymark tertiarytype url | |||
| 7. Description control | ||||
| e-Mail (login) | simone | |||
| update | ||||